Publications
This study describes the effects of the insertion of ISAba1 in the intrinsic bla ADC gene of an Acinetobacter baumannii isolate showing co-resistance to carbapenems and colistin. Isolate 52971 showed low ceftazidime MIC values due to the disruption of bla ADC-195 by this insertion sequence.
ISAba1 -mediated bla ADC disruption restores third-generation cephalosporin susceptibility in a clinical Acinetobacter baumannii isolate
Carolina S. Nodari, Felipe Alberto-Lei, et al.
Antimicrobial Agents and Chemotherapy, 2025
Staphylococcus epidermidis is an opportunistic commensal cutaneous biofilm-producing agent frequently causing musculoskeletal infections (MSI) with/without implants. This study was designed to evaluate phenotypic and genomic relatedness between commensal skin and infection-associated isolates.
Comparative genomic analysis of resistance and virulence genes in Staphylococcus epidermidis ...
Ingrid Nayara Marcelino Santos, Felipe Alberto-Lei, et al.
Scientific Reports, 2025
Klebsiella pneumoniae is an important pathogen that causes several human infections, which is currently among the main bacterial species of clinical importance. This study detected virulent strains causing intestinal and extraintestinal infections.
Detection of virulent Klebsiella pneumoniae strains causing intestinal and extraintestinal infections...
Tiago Barcelos Valiatti, Pedro Henrique Soares Nunes, et al.
Brazilian Journal of Microbiology, 2024
This retrospective study aimed to investigate the impact of the emergence of new variants and the epidemiological scenario on hospitalization rates of unvaccinated children (0-12 years) in Brazil. The death rate was 1.9%, with comorbidities playing a significant role.
Impact of Variants, Epidemiological Trends, and Comorbidities on Hospitalization Rates...
Danielle Dias Conte, Rai André Silva Watanabe, et al.
Influenza and Other Respiratory Viruses, 2024
This study aims to report the most common signs and symptoms in children infected by seasonal respiratory viruses and those infected by COVID-19, providing information about the signs and symptoms to healthcare professionals.
Respiratory virus detection among healthcare professionals with signs and symptoms of COVID-19...
G. Barbosa, F. Alberto-Lei, A.P.C. Chaves, et al.
Public Health, 2024
Objectives: To characterize a novel acquired MBL, BIM-1, in a Pseudomonas #2 (subgroup P. guariconensis ) strain isolated from the Aurá river located in the Brazilian Amazon hydrographic basin. WGS analysis revealed a novel acquired MBL-encoding gene, bla BIM-1.
Genetic and biochemical characterization of BIM-1, a novel acquired subgroup B1 metallo-β-lactamase...
Cintya O. Souza, Rodrigo Cayô, et al.
Journal of Antimicrobial Chemotherapy, 2023
Since its first report, the class A Brazilian Klebsiella carbapenemase (BKC) has been detected only among Enterobacterales isolates from Brazilian hospitals. In this study, we characterized a multidrug-resistant Pseudomonas juntendi clinical isolate and identified a 43.3-kb plasmid carrying bla BKC-1.
Characterization of a Carbapenem-Resistant BKC-1-Producing...
Felipe Alberto-Lei, Carolina S. Nodari, et al.
Antimicrobial Agents and Chemotherapy, 2022
Trichosporon spp. are constituents of the normal flora of humans that can cause both superficial and invasive infections, mainly in immunocompromised and immunocompetent hosts, respectively. Here, we report a case of Trichosporon asahii causing subcutaneous fungal infection (SFI) in an immunocompetent patient after carpal tunnel surgery.
Trichosporon asahii causing subcutaneous mycoses in an immunocompetent patient: case report and a minireview
Wdson Luis Lima Kruschewsky, Felipe Alberto-Lei, et al.
Brazilian Journal of Microbiology, 2022